| 1 |  Lionel MessiPenalty goals: 4 |  Barcelona | 36 |
| 2 |  Karim BenzemaPenalty goals: 3 |  Real Madrid | 21 |
| 3 |  Luis SuárezPenalty goals: 4 | Barcelona | 21 |
| 4 |  Iago AspasPenalty goals: 5 |  Celta de Vigo | 20 |
| 5 |  Cristhian StuaniPenalty goals: 5 |  Girona | 19 |
| 6 |  Wissam Ben YedderPenalty goals: 2 |  Sevilla | 18 |
| 7 |  Borja IglesiasPenalty goals: 3 |  Espanyol | 17 |
| 8 |  Antoine GriezmannPenalty goals: 3 |  Atlético de Madrid | 15 |
| 9 |  Raúl de TomásPenalty goals: 0 |  Rayo Vallecano | 14 |
| 10 |  Jorge MolinaPenalty goals: 2 |  Getafe | 14 |
| 11 |  Jaime MataPenalty goals: 4 | Getafe | 14 |
| 12 |  CharlesPenalty goals: 6 |  Eibar | 14 |
| 13 |  Iñaki WilliamsPenalty goals: 0 |  Athletic Club | 13 |
| 14 |  Maxi GómezPenalty goals: 1 | Celta de Vigo | 13 |
| 15 |  Roger MartíPenalty goals: 2 |  Levante | 13 |
| 16 |  Mikel OyarzabalPenalty goals: 3 |  Real Sociedad | 13 |
| 17 |  Pablo SarabiaPenalty goals: 1 | Sevilla | 12 |
| 18 |  José Luis MoralesPenalty goals: 3 | Levante | 12 |
| 19 |  Willian JoséPenalty goals: 5 | Real Sociedad | 11 |
| 20 |  Karl Toko EkambiPenalty goals: 0 |  Villarreal | 10 |
| 21 |  Ezequiel ÁvilaPenalty goals: 1 |  Huesca | 10 |
| 22 |  André SilvaPenalty goals: 0 | Sevilla | 9 |
| 22 |  Youssef En-NesyriPenalty goals: 0 |  Leganés | 9 |
| 24 |  PortuPenalty goals: 1 | Girona | 9 |
| 25 |  Giovani Lo CelsoPenalty goals: 2 |  Real Betis | 9 |
| 25 |  Jonathan CalleriPenalty goals: 2 |  Alavés | 9 |
| 25 |  Raúl GarcíaPenalty goals: 2 | Athletic Club | 9 |
| 28 |  Dani ParejoPenalty goals: 5 |  Valencia CF | 9 |
| 29 |  Ángel RodriguezPenalty goals: 0 | Getafe | 8 |
| 29 |  Gerard MorenoPenalty goals: 0 | Villarreal | 8 |
| 29 |  Ousmane DembéléPenalty goals: 0 | Barcelona | 8 |
| 29 |  RodrigoPenalty goals: 0 | Valencia CF | 8 |
| 33 |  Gareth BalePenalty goals: 1 | Real Madrid | 8 |
| 34 |  Santi MinaPenalty goals: 0 | Valencia CF | 7 |
| 34 |  Sergi EnrichPenalty goals: 0 | Eibar | 7 |
| 36 |  Iker MuniainPenalty goals: 1 | Athletic Club | 7 |
| 37 |  Sergio CanalesPenalty goals: 2 | Real Betis | 7 |
| 38 |  Álvaro MorataPenalty goals: 0 | Atlético de Madrid | 6 |
| 38 |  JoaquinPenalty goals: 0 | Real Betis | 6 |
| 38 |  Kévin GameiroPenalty goals: 0 | Valencia CF | 6 |
| 38 |  Loren MorónPenalty goals: 0 | Real Betis | 6 |
| 38 |  Munir El HaddadiPenalty goals: 0 | Sevilla | 6 |
| 43 |  Brais MéndezPenalty goals: 1 | Celta de Vigo | 6 |
| 43 |  Carlos BaccaPenalty goals: 1 | Villarreal | 6 |
| 43 |  Guido CarrilloPenalty goals: 1 | Leganés | 6 |
| 46 |  Enes ÜnalPenalty goals: 3 |  Real Valladolid | 6 |
| 47 |  Sergio RamosPenalty goals: 5 | Real Madrid | 6 |
| 48 |  Borja BastónPenalty goals: 0 | Alavés | 5 |
| 48 |  Enric GallegoPenalty goals: 0 | Huesca | 5 |
| 48 |  Gonçalo GuedesPenalty goals: 0 | Valencia CF | 5 |
